Mechanism of Action: How Forskolin Supports Healthy Weight Management
Forskolin helps support healthy weight management by promoting a balanced energy metabolism.
Its primary activity is the non-adrenergic activation of adenylate cyclase, an enzyme that increases the levels of cyclic adenosine monophosphate (cAMP)– a key cellular messenger.
cAMP-Driven Effects Include:
Supports energy expenditure:
Higher cAMP levels are associated with increased metabolic activity and thermogenesis, which may help the body use energy more efficiently.
Promotes lean body composition:
cAMP helps facilitate hormone-signaling pathways involved in maintaining healthy body composition.
Supports fat breakdown pathways:
cAMP activates protein kinase, which in turn supports the activity of hormone-sensitive lipase, an enzyme that helps break down stored triglycerides.
Helps convert white fat to metabolically active brown fat:
As described in Sabinsa’s patent, forskolin supports pathways linked to the browning of white adipose tissue, which may help the body burn additional calories.