(Badmaev V, Majeed M, Conte A, Parker JE (2002) Diterpene forskolin (Coleus forskohlii, Benth.): A Possible new compound for reduction of body weight by increasing lean body mass. NutraCos. March/April, 6-7)
In an eight week, pilot open field study, six overweight women received 500 mg ForsLean® corresponding to 50 mg forskolin/day. Their body composition was determined by bioelectrical impedance analysis. ForsLean was prepared in the form of two-piece hard shell capsules. Each capsule contained 250 mg of the extract standardized for 10% forskolin. The participants were instructed to take one capsule in the morning and one in the evening, half an hour before a meal. They were asked to maintain their previous daily physical exercise and eating habits. In addition, physical activity was monitored based on a questionnaire before and during the trial.
During the 8 week trial the mean values for body weight and fat content were significantly decreased, whereas lean body mass was significantly increased as compared to the baseline (Wilcoxon matched pairs test). Weight loss was statistically significant (p<0.05) after 4 and 8 weeks and the mean amounted to 4.3 and 9.17 lbs respectively. The body fat values expressed as % body fat were: 0 weeks 33.63 ± 3.02, 4 weeks 30.10 ± 4.34 (statistically not significant or n.s.), and 8 weeks 25.88 ± 4.77 (p<0.05). The lean body mass values expressed as % lean body mass were: 0 weeks 67.07 ± 3.02, 4 weeks 69.90 ± 4.34 (n.s.), and 8 weeks 74.13 ± 4.77 (p<0.05) (Figure 3).
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